Z. Zhang

This study identifies Schisandrin B as a potential treatment for male infertility by improving sperm count, mobility, and reproductive ability in a mouse model.

This study links cellular virological stages in chronic hepatitis B to liver fibrosis progression through spatial and functional analysis of viral and host gene expression.

The paper introduces a microtubule probe that enables correlative super-resolution fluorescence and electron microscopy to study microtubule ultrastructure.

The paper identifies activators and inhibitors of UDP-glucose dehydrogenase Ugd in E. coli and shows its role in swarming behavior.

The paper detects hydrogen evolution and absorption in plasma membrane vesicles of higher plants using spectrophotometry, gas chromatography, and H2 sensors, revealing bidirectional H2 activity.

The study links indoor microbial communities in university dormitories to asthma symptoms, finding specific taxa from different ecological niches are associated with increased or protective effects on asthma.

This study identifies eight distinct evolutionary lineages in the common pheasant, revealing regionally divergent drivers of diversification and suggesting the species should be split into three species.

This study describes a method to expand pancreatic islet clusters in vitro using hormones and chemicals, resulting in functional islet-like structures with cell type markers.

This study isolates and characterizes ten novel pelagiphages infecting Pelagibacter strains, revealing their genetic diversity, global distribution, and ecological significance.

This study examines the molecular evolution of Toll-like receptor genes in birds, finding that positive selection is linked to migration, parental care, and body size.

This study identifies the key interaction region and phosphorylation site of EcaICE1 that mediates its interaction with EcaHOS1 in Eucalyptus.

This study identifies the transcription activation domain and interaction region of EcaICE1 with EcaSIZ1 in Eucalyptus camaldulensis, revealing potential SUMOylation pathway similarities to Arabidopsis thaliana.

This study compares microbial composition in floor and air dust from university dormitories, showing significant differences that affect downstream microbiome analysis.

This paper introduces a drug discovery platform called SPEED that uses epitope editing to screen small molecules for altering antibody-epitope interactions and validates its application for Aβ species.

The paper develops a luciferase-based murine model and cell assay to evaluate the efficacy of MetRS inhibitor 1717 against Giardia lamblia, showing its potent in vivo activity.

This study analyzes 2,152 antibody repertoires to identify key features of B cell biology, revealing gene usage patterns, sex preferences, and mutability mechanisms in the antibody repertoire.

The paper introduces a pinhole optical trap that extends photobleaching lifetime by separating trap light from fluorescence illumination using wavefront engineering.

This study identifies TMEM-131 family proteins as conserved regulators of collagen assembly and secretion across species, showing their role in ER stress and collagen production.

This study identifies GATA3 and AP1-driven enhancer reprogramming as a mechanism promoting phenotypic plasticity and endocrine resistance in breast cancer.

This paper proposes a strategy to select crop varieties based on yield factors and meteorological predictions, showing 70% and 50% success rates in two pilot regions for soybean variety selection.

This study investigates the role of ASK1/p38-mediated NLRP3 inflammasome signaling in diabetic retinopathy, showing its contribution to inflammation and aberrant retinal angiogenesis.

This study shows that CHL1 overexpression reverses chemoresistance to cisplatin and paclitaxel in lung cancer by inhibiting the Akt pathway.

This study develops a rapid and efficient cowpea transformation system using embryonic axis explants, achieving transgenic shoot frequencies of 4.5 to 37%.

The paper investigates 5-hydroxymethylcytosine (5hmC) as a potential biomarker for pancreatic cancer, showing distinct distributions in tumor and adjacent tissues.

The paper shows that iron-deficiency and estrogen increase transferrin, leading to hypercoagulability and worsened ischemic stroke.

This study identifies ANP32A and ANP32B as essential for influenza A virus polymerase activity, showing species-specific roles and mutations affecting viral replication.

The paper shows that Streptomyces coelicolor colonies use division of labour to enhance antibiotic production by generating specialized mutants that trade individual fitness for increased secondary metabolite diversity and yield.

The paper investigates how protein-protein interactions in E. coli's PTS system affect sugar transport and phosphorylation, showing both enhancement and inhibition of different PTS permeases.

The paper shows Tyr1 phosphorylation directs P-TEFb to phosphorylate Ser2 on RNA polymerase II CTD, altering its specificity and expanding CTD modification coding potential.

This study evaluates the efficacy and adverse effects of antibiotics in treating M. abscessus pulmonary disease, finding that four antibiotics correlate with treatment success but are associated with severe side effects.