C. Wang

This study shows Hsp70 chaperones TDP-43 in liquid-like phase, preventing its aggregation and maintaining dynamic nuclear bodies under stress.

This paper uses UAV-captured multispectral images to predict sugarcane canopy nitrogen content and irrigation levels using PLS, BPNN, ELM, and SVM models.

The paper develops a novel isothermal amplification method (LMCP) for detecting Oryza sativa ITS with higher sensitivity and speed compared to LAMP.

This study identifies 24 FDA-approved compounds that inhibit SARS-CoV-2 replication, with five showing high safety indices and blocking S protein-mediated cell fusion.

This paper evaluates the antiviral efficacy of GS441524 and GC376 combination therapy against SARS-CoV-2 in a mouse model, showing synergistic effects and protection with low-dose combined treatment.

This paper reports a monoclonal antibody, 3E8, that blocks multiple coronaviruses by targeting ACE2, showing broad-spectrum activity against SARS-CoV-2 variants and other coronaviruses.

This paper describes a protocol for inducing collagen-induced arthritis (CIA) in mice using bovine collagen type II and Freund's adjuvants, and reports associated enteritis and arthritis outcomes.

This study uses pH-sensitive fluorescent protein to track vacuolar pH changes during cell-in-cell mediated death, revealing distinct pH dynamics in entotic and apoptotic death and their implications for cancer treatment.

This review examines 12 studies on the effects of audible sound on cell cultures, finding varied outcomes like enhanced migration and differentiation but noting methodological inconsistencies.

This study identifies genetic determinants of COVID-19 drug efficacy using genome-wide CRISPR screens, revealing genes involved in drug metabolism and immunosuppressive effects.

This study isolates two cross-reactive monoclonal antibodies against multiple Betacoronaviruses, identifying a conserved vulnerable site on the spike protein.

This study uses TRACE-seq to analyze single throat swabs, integrating SARS-CoV-2 genome, microbiome, antibiotic resistance, and host response data.

This paper introduces a distance geometry method for protein structure determination using structural similarity initialization, achieving high accuracy with limited distance data.

This study shows heat stress inhibits meiotic recombination in Arabidopsis by reducing DSB formation and homolog synapsis, affecting chromosome axis stability and recombinase levels.

This paper identifies a human monoclonal antibody, 47D11, that targets a conserved hydrophobic pocket in the SARS-CoV-2 RBD, revealing its structural basis for neutralization and potential therapeutic use.

This study analyzes the transcriptome of potato leaves infected with Alternaria solani to identify gene expression changes and hormone responses associated with disease resistance.

This study identifies how PTP-MEG2 regulates exocytosis by dephosphorylating specific sites on NSF, DYNAMIN2, and MUNC18-1, revealing distinct structural mechanisms for substrate recognition.

This study analyzes cerebrospinal fluid from healthy pregnant women and finds no evidence of a detectable microbial community after accounting for contamination.

The paper introduces COMPACT, a technique that significantly increases tissue access volume for deep brain imaging, enabling multiregional calcium imaging of deep brain functions associated with sleep.

The paper investigates the genomic basis of symbiosis in a vent snail, revealing a tripartite holobiont system involving host, endosymbionts, and gut microbiota, highlighting metabolic flexibility and mutualistic interactions.

This study identifies a Krt5-BMP4 mechanosignaling pathway that regulates histone modifications and blastema cell remodeling during zebrafish heart regeneration.

This study evaluates SOX2, OCT4, and NANOG expression in ovarian cancer cell lines under 2-D and 3-D culture conditions, finding SOX2 is more strongly associated with tumor-initiating cells and chemotherapy resistance.

The paper identifies azetidine derivatives that kill Mycobacterium tuberculosis without resistance by inhibiting mycolate assembly, showing a novel mode of action and favorable pharmacological profiles.

This paper demonstrates that engineered T cell libraries with CAR constructs can recognize nonself-antigens, expand clonally, persist, and show immunologic memory against tumors in murine models.

This paper develops potent anti-SARS-CoV-2 DARPin therapeutics with low picomolar neutralization efficacy and reports their protective efficacy in a hamster model.

This study shows that high-dose convalescent plasma or monoclonal antibodies protect hamsters from SARS-CoV-2-induced lower respiratory disease, but lower doses are ineffective.

This paper investigates how Esteya vermicola colonizes pine trees and interacts with Bursaphelenchus xylophilus, revealing specific infection mechanisms and colonization patterns in healthy and infected trees.

The paper identifies public antibody clones in the human repertoire, including virus-neutralizing and anti-PD1 clones, and introduces a tool for analyzing Rep-seq data.

This paper develops membrane nanoparticles from ACE2-rich cells that effectively block SARS-CoV-2 infection by trapping the viral S1 protein and inhibiting its interaction with host cells.