J. Huang

This study examines how Salmonella develops resistance to enrofloxacin under varying sub-inhibitory concentrations, identifying gene expression changes and mutations involved in resistance.

The paper identifies two circRNAs whose m6A methylation synergistically promotes pulmonary fibrosis by targeting eIF4A3, mediated by METTL3.

This study uses recombinant Lloviu virus to investigate replication mechanisms and host interactions of an uncultured filovirus related to Ebola.

This study uses iPSC-derived airway cells to model SARS-CoV-2 infection, showing multiciliated cells as primary targets and demonstrating antiviral responses to remdesivir and camostat methylate.

This study identifies 187 DNA/RNA differences in 36 wheat genes associated with Fusarium head blight, showing their role in regulating FHB response through structural changes and miRNA interactions.

This study examines antibody responses to SARS-CoV-2 mRNA vaccines in naive and previously infected individuals, finding robust IgG and varying neutralizing antibody levels against different variants.

This study investigates how two first-generation MsbA inhibitors, TBT1 and G247, induce opposite allosteric effects by binding to distinct sites in the transmembrane domains.

The paper shows that CRISPR-Cas13 can reduce RNA in plants without the Cas13 protein, using a mechanism similar to RNAi.

This study determines the structure of post-fusion hMPV B2 F protein, assesses its receptor binding and immunogenicity, and shows it induces neutralizing antibodies against multiple hMPV strains.

The paper shows lung epithelial cells can produce TD-Ag-specific antibodies, dependent on CD4+ T cells, challenging the notion that B cells are the sole source of such antibodies.

This paper identifies PRC2-mediated epigenetic repression as critical for regulating gene expression during biotrophic growth in M. oryzae, with Pmk1 coordinating this process by modulating Suz12.

This study identifies three ultrapotent SARS-CoV-2 neutralizing antibodies effective against B.1.351 variants, showing synergistic effects and protective efficacy in mice.

The paper identifies simeprevir as a potent inhibitor of SARS-CoV-2 replication that synergizes with remdesivir in vitro.

This study evaluates the impact of phase resolution strategies on phylogenomic analyses under the multispecies coalescent model, finding that random phasing leads to biased parameter estimates.

This study shows that combining anti-GD2 and anti-CD47 antibodies enhances anti-tumor responses by recruiting macrophages and disrupting the GD2:Siglec-7 interaction in GD2+ cancers.

The paper observes actomyosin contractile instability in isolated cytokinetic rings and shows myosin II turnover prevents catastrophic aggregation and fracture.

This study shows SUMOylation of GMFB increases its stability and trans-localization, upregulating inflammatory pathways in RPE cells under oxidative stress and inflammation.

This study evaluates S-Trimer, a subunit vaccine candidate for COVID-19, showing it induces protective immunity in nonhuman primates with adjuvants.

This study identifies PAQR3 as a predictor of epirubicin response in TNBC and shows that MAPK inhibition can reverse resistance caused by miR-138-5p-mediated PAQR3 downregulation.

This study shows Talaromyces marneffei induces M2 macrophage polarization by downregulating SOCS3 and activating TLR9, enhancing fungal survival.

The paper isolates human monoclonal antibodies against pneumococcal proteins PhtD and PspA, showing protection against pneumococcal infection in mice.

This study shows that RIPK3 phosphorylation at S165/T166 switches its function from necroptosis to apoptosis, driving corpus luteum regression via PGF2-induced apoptosis.

This paper introduces Nanotraps, functionalized nanoparticles that block SARS-CoV-2 infection by inhibiting spike protein-ACE2 interaction and triggering macrophage-mediated viral clearance.

This study identifies SiCEP3, a C-terminally encoded peptide from Setaria italica, which promotes ABA import and signaling by inhibiting receptor kinase activity under abiotic stress.

The paper identifies an epigenetic mechanism regulating AXL-positive/Erlotinib-resistant cells through miR-335 expression, suggesting combinatorial therapies for EGFR-mutated NSCLC.

This study investigates the neuroprotective role of CTRP1 in TBI rats, finding it reduces inflammation and modulates autophagy through mTOR activation.

This study evaluates DHEA extract from sweet potato on C. elegans lifespan, finding it extends life by 13.60% but not via calorie restriction, and suggests antioxidant and daf-16 activation mechanisms.

This study develops a high-throughput method using near-infrared spectroscopy to assess sugarcane stalk quality, achieving high prediction accuracy with RPD values up to 6.3.

This study shows that A-to-I RNA editing in Xanthomonas oryzae enhances iron uptake by modifying the xfeA gene, improving bacterial competitiveness in iron-limited environments.

This paper develops a photothermal nanoparticle conjugated with neutralizing antibodies to capture and inactivate SARS-CoV-2, showing efficient viral capture, photothermal effect, and inhibition of viral entry.