X. Liu

This paper identifies and characterizes Fnr paralogs in Paenibacillus polymyxa WLY78, showing their roles in regulating nitrogen fixation and anaerobic metabolism through gene expression changes.

This study isolates multiple SARS-CoV-2-neutralizing antibodies through site-directed screening, showing potent protection against virus infection.

This study shows that NRT1.1 in Arabidopsis roots coordinates with K+ channels to regulate uptake and allocation of potassium.

This study shows that transient hyperglycemia causes long-term vascular endothelial dysfunction and delayed wound healing through DNMT1-mediated Ang-1/NF-κB pathway activation.

This study identifies bosutinib as a radiosensitizer for breast cancer by targeting eIF4G1, enhancing radiation efficacy and reducing drug dosage.

A hidden layer of host immunity against non-pathogenic microbes leads to plant incompatibility with beneficial rhizobacteria.

This study shows Mg2+ promotes bone regeneration initially by modulating macrophage activity but later inhibits bone formation through NF-κB activation and reduced hydroxyapatite precipitation.

This study uses CRISPRi-seq to identify genetic factors important for Streptococcus pneumoniae pneumonia, revealing a critical bottleneck at 48 h post-infection and gene fitness differences between in vitro and in vivo conditions.

This study maps 3D genome organization in normal and AML haematopoietic stem cells, finding increased chromatin loops to oncogenes in AML and identifying MEIS1 and HOXA9 as key oncogenes regulated by these interactions.

This paper reports the cryo-EM structure of the C9ORF72-SMCR8-WDR41 complex, revealing its role as a GAP for Rab8a and Rab11a.

The paper investigates how vegetation and microbes interact to preserve organic matter in wooded peatlands, finding that slow-growing microbes and plant-induced recalcitrant carbon reduce carbon loss despite climate stressors.

This study shows Carmofur inhibits SARS-CoV-2 main protease by covalently binding to Cys145 and occupying the S2 subsite, with an EC50 of 24.30 M in cell-based viral replication assays.

PM2RA detects and quantifies microbial relationship alterations between healthy and diseased states, showing higher specificity and sensitivity than co-occurrence-based methods.

OptiFlex improves animal pose estimation by integrating optical flow and a flexible model, achieving better accuracy across four species.

The paper was withdrawn due to the authors no longer supporting some conclusions.

The paper compares silicone and cotton swabs for RNA extraction in COVID-19 testing, finding silicone swabs yield higher RNA concentration and quality.

This study classifies and analyzes the expression of heat shock proteins in wheat infected with powdery mildew and stripe rust, revealing structural diversity and differential expression patterns.

This study designs, synthesizes, and evaluates two peptidomimetic aldehydes as antiviral drug candidates targeting SARS-CoV-2 main protease, showing potent inhibition and anti-infection activity.

This study shows Nrf1 represses tumor growth by inhibiting Wnt/β-catenin signaling and other pathways through ubiquitination of β-catenin and regulation of key genes.

This paper applies federated learning to drug discovery, showing it improves prediction accuracy over centralized training with biased and small datasets.

This study shows that rhesus macaques infected with SARS-CoV-2 are protected from reinfection during early recovery, likely due to enhanced neutralizing antibodies.

This study identifies the COMPASS-like complex in M. oryzae and shows it regulates H3K4me3-mediated gene expression critical for fungal development and pathogenesis.

This study shows that SARS-CoV-2 can cause mild COVID-19 in rhesus macaques through conjunctival inoculation, with distinct viral dispersion patterns compared to intratracheal inoculation.

This study isolates a halotolerant Pseudomonas aeruginosa strain capable of degrading waste cooking oil and producing rhamnolipids, achieving high degradation rates and surfactant yields.

The paper measures SARS-CoV-2 RNA concentration in aerosols from different areas of Wuhan hospitals during the COVID-19 outbreak and finds that aerosol transmission is possible under certain conditions.

This study identifies SIZ1-mediated SUMOylation of ROS1 as a mechanism enhancing ROS1 stability and promoting active DNA demethylation in Arabidopsis.

Infected macrophages use alveolar epithelium to reprogram bystander myeloid cells via IL-1 and GM-CSF, enhancing antibacterial inflammation.

This study identifies a non-hypermucoviscous ST11 hypervirulent K. pneumoniae strain lacking classical virulence factors, showing increased virulence through ampR and WcaJ mechanisms.

This study shows artesunate interacts with the vitamin D receptor to reverse sepsis-induced immunosuppression by enhancing autophagy and modulating NF-κB activity.