Y. Sun

This study produces and tests an F(ab')2 fragment against SARS-CoV-2 RBD, showing potent in vitro neutralization with an EC50 of 0.07 g/ml.

This study analyzes plastome sequences from Gentianeae to show gene tree discordance and evolutionary rate heterogeneity among plastid genes, suggesting the need for more nuanced phylogenomic approaches.

The paper was withdrawn due to the authors no longer supporting some conclusions.

This study shows senescent stromal cells release sEVs that promote cancer drug resistance via SIRT1 loss, and suggests targeting SIRT1 could prevent this resistance.

The paper analyzes CD45 isoforms in T cells from liver cancer patients to show their role in T cell heterogeneity and function.

This study identifies mitochondrial complex II disruption in intestinal epithelial cells as a key driver of T-cell mediated intestinal immunopathology across multiple disease models.

This study analyzes plant responses to water stress through a global meta-analysis, finding that ROS overproduction is a primary response mechanism and that plants acclimate over time.

This paper develops a cardiac fibrosis-on-a-chip model that recapitulates fibrosis hallmarks and enables drug screening for anti-fibrotic therapies.

This study shows that invasive common ragweed populations can rapidly evolve in response to climate warming within a single generation, with greater genetic divergence and phenotypic convergence under warming conditions.

The paper compares two phylogeographic models, showing that sampling bias affects Brownian Motion Phylogeography (BMP) and that the spatial Lambda-Fleming-Viot process (LambdaFV) is more robust but applicable to different scenarios.

The paper uses single-cell RNA sequencing to analyze stomatal lineage cell development in Arabidopsis, identifying new marker genes and transcriptional networks.

This study identifies strain-level features of the mouse gut microbiota using metagenome-assembled genomes, revealing distinct genomic and functional characteristics compared to human gut microbes.

This study isolates and expands SOX9+ renal epithelial cells from adult humans, showing their ability to regenerate kidney tissue in mice.

The study links indoor microbial communities in university dormitories to asthma symptoms, finding specific taxa from different ecological niches are associated with increased or protective effects on asthma.

This paper introduces a DNA-based fluorescent probe, DNAMeter, to quantify intercellular tensile forces through real-time imaging and fluorescence signal activation.

This study determines the cryo-EM structure of a novel α-synuclein fibril formed by the E46K mutation, showing structural changes and altered stability compared to wild-type fibrils.

This study compares microbial composition in floor and air dust from university dormitories, showing significant differences that affect downstream microbiome analysis.

This study shows LIMD1 phase separation at focal adhesions regulates force sensing and durotaxis by controlling FA dynamics in response to mechanical cues.

This study identifies TIGAR as a driver of metabolic remodeling in ESCC, showing that targeting the glutamine pathway improves therapeutic outcomes in TIGAR-overexpressed tumors.

This study examines changes in IL-10 expression in myocardial infarction and its association with macrophage activation and cardiomyocyte apoptosis over time.

This study shows that synonymous SNPs in viral genes of WSSV reduce RNAi effectiveness by causing siRNA-target mismatches, allowing the virus to evade host immunity.

The paper characterizes the interactions between the AAUAAA polyadenylation signal and protein factors using fluorescence polarization, showing specific affinity and sequence requirements for recognition.

This paper introduces CLEAR-dPCR, a lossless and contamination-free digital PCR technology that improves accuracy and dynamic range compared to existing platforms.

This study compares clathrin-mediated endocytosis in budding and fission yeast, finding conserved mechanisms and species-specific adaptations in actin assembly and membrane invagination.

This study identifies widespread arginine phosphorylation in human cells using a novel phosphoproteomic workflow, revealing 152 high-confidence sites across 118 proteins.

This study identifies stable reference genes for RT-qPCR normalization in Hypericum perforatum across tissues, developmental stages, and stress conditions.

This study identifies a distinct metabolic and immune phenotype in women with right-sided colon cancer through gene expression analysis of public datasets.

The paper shows nuclear actin enhances RNA polymerase II clustering during inducible transcription, facilitating rapid gene expression in response to stimuli like serum and interferon-gamma.

The paper determines the absolute protein stoichiometry of carboxysomes and reveals their organizational variability in response to microenvironmental changes.

This study identifies mutant p53's role in promoting clonal hematopoiesis by modulating the EZH2-mediated epigenetic pathway.