W. Zhang

This paper describes a laboratory module using C. elegans to teach RNA interference and codon optimization through fluorescence microscopy and quantitative image analysis.

This study identifies structural variants in Brassica oleracea genomes that contribute to morphological divergence between cauliflower and cabbage.

This paper introduces a hierarchical point process model for spatial capture-recapture data using non-invasive genetic sampling, estimating wolverine density without data augmentation.

The paper analyzes phorbol ester distribution in Jatropha curcas tissues and links it to gene expression under various stresses.

This study shows vitexin inhibits melanoma cell invasion and metastasis by targeting the STAT3 signaling pathway.

This study analyzes cerebrospinal fluid from healthy pregnant women and finds no evidence of a detectable microbial community after accounting for contamination.

This study shows that patient-derived NFE2L2 mutants drive aggressive hepatoblastomas in mice by accelerating tumor growth and promoting necrosis and cyst formation.

The paper identifies mutanofactin-697, a secondary metabolite from S. mutans, which promotes biofilm formation by increasing bacterial hydrophobicity and adhesion.

The paper analyzes SARS-CoV-2 quasispecies structure using SMRT sequencing, revealing a One-King model with dominant and minor haplotypes and their evolutionary dynamics.

This study shows Arabidopsis myosin XIK interacts with the exocyst complex to facilitate vesicle tethering during exocytosis, revealing a role in secretory processes in plants.

This study shows SARS-CoV-2 uses the SR-B1-mediated HDL uptake pathway alongside ACE2 for entry, and blocking this pathway inhibits infection.

This study identifies metabolic dysfunction and mitochondrial impairment in SLC4A11-deficient corneal endothelial cells as the cause of dystrophy.

The paper discovers a new family of natural products, clostyrylpyrones, from Clostridium roseum and proposes their polyketide synthase-based biosynthesis mechanism.

This study shows that PCK1 deficiency increases O-GlcNAcylation and promotes HCC growth under glucose deprivation by enhancing CHK2 activity.

This study genetically modifies human macrophages with CARs to target SARS-CoV-2, showing that CARMERTK macrophages reduce viral load without increasing proinflammatory cytokines.

The paper develops a fluorescent biosensor for L-2-hydroxyglutarate (L-2-HG) using LhgR, a transcription factor that recognizes L-2-HG, and demonstrates its application in monitoring L-2-HG levels in bacterial and human cells.

This study tracks the dynamic localization of Japanese encephalitis virus (JEV) in mouse brain nuclei over time, revealing its progression from thalamus and medulla oblongata to widespread distribution in the central nervous system.

The paper shows that NORTIA accumulation at the filiform apparatus is essential for pollen tube reception in Arabidopsis thaliana.

This study reports the largest sequenced plant genome, Paris polyphylla var. yunnanensis, and identifies genes involved in polyphyllin biosynthesis.

This study investigates the evolution, cross-species transmission, and origin of bat coronaviruses in China using sequence data and Bayesian analysis.

This study identifies MMD-associated RNF213 SNPs as dominant negative alleles that impair ubiquitylation, suggesting reduced E3-ligase activity as central to MMD pathogenesis.

The paper shows that viral DNA packaging motors switch between helical and planar symmetry to translocate double-stranded DNA.

This study investigates ion and water permeation mechanisms of the SARS-CoV-2 E protein channel using in silico methods, revealing hydrophobic gates and voltage-dependent behavior.

This study predicts lncRNA-encoded small peptides in glioma and analyzes their oligomer channel function using in silico methods.

This study shows that blocking CTLA-4 reverses Treg cell suppression of anti-TB T-cell responses in tuberculosis patients.

This study expands the known diversity of magnetosome biogenesis in bacteria by analyzing new genomes and revealing an early evolutionary origin of magnetic nanoparticle formation.

This study shows that lung-stage schistosome infection reduces allergic airway inflammation by increasing allergen-specific Treg cells that inhibit IgE and Th2 cytokine production.

The paper withdraws its manuscript due to the need for further experiments to validate conclusions.

This study compares non-Cochrane nursing systematic reviews with their PROSPERO-registered protocols, finding widespread discrepancies with few explanations.

This study uses live-cell 3D single-molecule tracking to show that the NuRD complex decompacts chromatin and alters enhancer dynamics by increasing their movement and reducing time in a fast-diffusing state.